In a sci-fi horror story I'm imagining (because I'm too lazy to write it.) The Evil scientist-doctor doesn't want to to be wrong about his promise that the unvaccinated will be dying off this winter... so another top secret lab somewhere "has bat-soup at the market" and we get a whole new man-made virus (and from what I've read there are possible signs that point to the first strain being man-made) and this time it's targeting the non-vaccinated.
If Dr Evil can pull it off the remaining citizens will do whatever they are told to do to stay alive.
I think I can get Kurt Russell to play the grizzled commander of The Wolverines, who save the day at the end ...
but that would involve writing it all down.